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    RenBiologics Assets Brochure

    January 26, 2024
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    • Fully Human Antibody Library

    • Preclinical PCC and Clinical Assets

    • Antibody Assets Licensing & Co-Development

    Biocytogen’s fully human antibody library is comprised of 400K+ sequences targeting 900+ antigens, applicable to multiple therapeutic areas. These antibodies were generated using proprietary RenMice® strains, each engineered to lack a certain drug target gene. This fully human, hyperimmune, target-specific (HiTS) platform increases the likelihood that our antibodies have desirable characteristics, including:
    • Lower risk of immunogenicity
    • Cross-species recognition to facilitate preclinical efficacy and safety evaluation
    • High specificity, affinity and diversity, owing to the comprehensive coverage of immunoglobulin variable region genes in our RenMice models
    • Feasibility of assembly into various modalities, including bispecific antibodies (bsAbs)/engagers, bispecific ADCs (bsADCs), Hu-VHH Platform and TCR-mimic antibodies for your novel therapeutic application
    • Facilitates discovery for a comprehensive list of popular yet difficult drug targets, including cell membrane proteins, extracellular proteins, and intracellular proteins.