By Therapeutic Area

Cardiovascular and Cerebrovascular

Biocytogen has developed a series of humanized mouse models targeting PCSK9 and APOC3, along with cardiovascular and cerebrovascular disease models, to facilitate the evaluation of novel therapeutics.

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  • Cardiovascular and Cerebrovascular Model Introduction
  • Cardiovascular and Cerebrovascular Disease Models
  • Genetically Engineered Cardiovascular and Cerebrovascular Related Models

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    Cardiovascular and Cerebrovascular Model Introduction

    Cardiovascular and cerebrovascular diseases represent a major cause of morbidity and mortality in clinics. To improve diagnostics, and to discover and test novel preventive and curative therapies, experimental models that recapitulate human disease are appealing to the researchers worldwide.

    Biocytogen has developed a series of humanized mouse models targeting PCSK9 and APOC3, along with cardiovascular and cerebrovascular disease models, to facilitate the evaluation of novel therapeutics.

    Cardiovascular and Cerebrovascular Disease Models
    Hyperlipidemia/Atherosclerosis Mouse Models

    Humanized mouse models targeting PCSK9 and APOC3, and an atherosclerosis model based on ApoE KO mice, facilitate the evaluation of novel therapeutics.

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    Middle Cerebral Artery Occlusion (MCAO) Mouse Models

    The Middle Cerebral Artery Occlusion (MCAO) model is a widely used preclinical tool that replicates ischemic stroke in humans, making it ideal for preclinical studies.

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