C57BL/6-Cd133tm1(CD133)Bcgen/Bcgen • 111093
| Product name | B-hCD133 mice |
|---|---|
| Catalog number | 111093 |
| Strain name | C57BL/6-Cd133tm1(CD133)Bcgen/Bcgen |
| Strain background | C57BL/6 |
| Aliases | PROM1:AC133, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4 |
Targeting strategyGene targeting strategy. The full coding region sequences of mouse Cd133 gene was replaced by human CD133 counterpart gene sequences in B-hCD133 mice.
Protein expression analysis
CD133 expression analysis in homozygous B-hCD133 mice by flow cytometry. Bone marrow hematopoietic stem cell (Lin-/lowmSca1+mCD117+) were collected from wild-type mice (+/+) and homozygous B-hCD133 mice (H/H), and analyzed by flow cytometry with species-specific anti-CD133 antibody. Human CD133 was detectable in homozygous B-hCD133 mice.
