BALB/cAnN • 311118
| Product name | B-Luc A20 |
|---|---|
| Catalog number | 311118 |
| Strain name | BALB/cAnN |
| Strain background | BALB/cAnN |
| Aliases | Gt(ROSA)26Sor |
| Tissue | B lymphocyte |
| Disease | Reticulum cell sarcoma |
| Species | Mouse |
| Application | B-Luc A20 cell line can be used to evaluate anti-cancer drugs in reticulum cell sarcoma in vivo |
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DescriptionThis B-Luc A20 cell line expresses firefly luciferase as a marker of A20 cells. Fluorescence and luminescence can be observed in B-Luc A20 cells.
Targeting strategyGene targeting strategy for B-Luc A20 cells. The exogenous promoter and luciferase was inserted into the ROSA26 locus in murine.
In vitro luciferase activity of B-Luc A20 cells
Luminescence signal intensity of B-Luc A20 cells. Luminescence intensity was measured using the Bright-GloTM luciferase Assay. B-Luc A20 cells have a strong luminescence signal.
Quantitative imaging data & body weight changes
Tumor growth and in vivo imaging of B-Luc A20 cells. B-Luc A20 cells (5x105) were injected into the tail vein of wild-type BALB/c mice. Signal intensity and body weight were measured twice a week. (A) Imaging was performed twice a week. (B) Body weight (Mean ± SEM). B-Luc A20 cells can be used for in vivo efficacy evaluation.
Imaging analysis in vivo
