B-hCCL24 mice

C57BL/6N-Ccl24tm1(Ccl24)Bcgen/Bcgen • 111396

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B-hCCL22 mice
B-hCCL3 mice

B-hCCL24 mice

Product nameB-hCCL24 mice
Catalog number111396
Strain nameC57BL/6N-Ccl24tm1(Ccl24)Bcgen/Bcgen
Strain backgroundC57BL/6N
AliasesCCL24: Ckb-6, MPIF2, MPIF-2, SCYA24
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  • Targeting strategy
  • Phenotypic analysis

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      Targeting strategy

      Gene targeting strategy for B-hCCL24 mice. The exons 1-3 of mouse Ccl24 gene that encodes the full-length protein were replaced by human CCL24 exons 1-3 in B-hCCL24 mice.

      Protein expression analysis
      Strain specific CCL24 expression analysis in homozygous B-hCCL24 mice by ELISA. Serum were isolated from wild-type C57BL/6 mice (+/+) and homozygous B-hCCL24 mice (H/H), and analyzed by ELISA with species-specific CCL24 ELISA kit. Mouse CCL24 was detectable in wild-type mice (A). Human CCL24 was exclusively detectable in homozygous B-hCCL24 mice but not in wild-type mice (B).