B-hCD300E mice

C57BL/6N-Tg(RP11-354A1)1/Bcgen • 113070

B-hCD300A mice
B-hCD31 mice

B-hCD300E mice

Product nameB-hCD300E mice
Catalog number113070
Strain nameC57BL/6N-Tg(RP11-354A1)1/Bcgen
Strain backgroundC57BL/6N
NCBI gene ID342510
AliasesCD300LE, CLM-2, CLM2, CMRF35-A5, IREM-2, IREM2, PIgR-2, PIgR2

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  • Targeting strategy
  • Phenotypic analysis

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      Targeting strategy

      Gene targeting strategy for B-hCD300E mice. The full coding sequences of human CD300E gene that is driven by human CD300E promoter are inserted mouse genomic by BAC transgene(RP11-354A1 via SwaI ).

      Protein expression analysis in monocytes

      CD300E expression analysis in F1 B-hCD300E mice by flow cytometry. Blood cells were collected from wild-type C57BL/6 mice (+/+) and F1 B-hCD300E mice, and analyzed by flow cytometry with anti-CD300E antibody (BD Biosciences, 566315). hCD300E was exclusively detectable in monocytes in 1TG0020-0034 TG mice line.

      Protein expression analysis in macrophages

      CD300E expression analysis in F1 B-hCD300E mice by flow cytometry. Blood cells were collected from wild-type C57BL/6 mice (+/+) and F1 B-hCD300E mice, and analyzed by flow cytometry with anti-CD300E antibody (BD Biosciences, 566315). hCD300E was exclusively detectable in macrophages in 1TG0020-0034 TG mice line.

      Protein expression analysis in neutrophils

      CD300E expression analysis in F1 B-hCD300E mice by flow cytometry. Blood cells were collected from wild-type C57BL/6 mice (+/+) and F1 B-hCD300E mice, and analyzed by flow cytometry with anti-CD300E antibody (BD Biosciences, 566315). hCD300E was not detectable in neutrophils.