C57BL/6-Clutm1(CLU)Bcgen/Bcgen • 111430
| Product name | B-hCLU mice |
|---|---|
| Catalog number | 111430 |
| Strain name | C57BL/6-Clutm1(CLU)Bcgen/Bcgen |
| Strain background | C57BL/6 |
| Aliases | CLU (AAG4, APO-J, APOJ, CLI1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2, CLU) |
Tageting strategyGene targeting strategy for B-hCLU mice.
The exon 2-9 of mouse Clu gene that encode the full-length protein were replaced by human CLU exon 2-9 in B-hCLU mice.
Protein expression analysis
Strain specific CLU expression analysis in homozygous B-hCLU mice by ELISA. Serum were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hCLU mice (H/H), and analyzed by ELISA with species-specific CLU ELISA kit. Mouse CLU was detectable in wild-type mice. Human CLU was exclusively detectable in homozygous B-hCLU mice, but not in wild-type mice.
