B-NDG H2-K1/H2-D1 KO mice

NOD.CB17-PrkdcscidIL2rgtm1 BcgenH2-K1tm1 BcgenH2-D1tm1 Bcgen/Bcgen • 112256

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B-NDG H2-Ab1 KO mice
B-NDG hairless mice

B-NDG H2-K1/H2-D1 KO mice

Product nameB-NDG H2-K1/H2-D1 KO mice
Catalog number112256
Strain nameNOD.CB17-PrkdcscidIL2rgtm1 BcgenH2-K1tm1 BcgenH2-D1tm1 Bcgen/Bcgen
Strain backgroundB-NDG
AliasesH2-K1: H-2K, H-2K(d), H2-D1, H2-K, K-fH2-D1: H-2D, H2-D, H2-K1
ApplicationNo MHC class I molecule expression; Reduce GVHD and prolong the experimental window period; Improve the accuracy of efficacy verification
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  • Phenotypic analysis

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      Protein expression analysis

      Strain specific H2-Kb/H2-Db (α chain of MHC-I molecule) expression analysis in B-NDG mice and B-NDG H2-K1/H2-D1 KO mice by flow cytometry. Bone marrow, spleen and blood were collected from B-NDG mice and B-NDG H2-K1/H2-D1 KO mice, and analyzed by flow cytometry. Mouse H-2Kb/H-2Db was only detectable in B-NDG mice but not in B-NDG H2-K1/H2-D1 KO mice.