NOD.CB17-PrkdcscidII2rgtm1BcgenAlbtm1(ALB)Bcgen/Bcgen • 111982
Product name | B-NDG hALB mice |
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Catalog number | 111982 |
Strain name | NOD.CB17-PrkdcscidII2rgtm1BcgenAlbtm1(ALB)Bcgen/Bcgen |
Strain background | B-NDG |
Aliases | ALB:HSA, FDAHT, PRO0883, PRO0903, PRO1341 |
Application | Used for pharmacological or pharmacokinetic studies of drugs that utilize albumin to extend their half-life |
Strain specific ALB expression analysis in homozygous B-NDG hALB mice by ELISA. Serum was collected from B-NDG mice (+/+) and homozygous B-NDG hALB mice (H/H), and analyzed by ELISA with species-specific ALB ELISA kit. Mouse ALB was detectable in B-NDG mice (A). Human ALB was exclusively detectable in homozygous B-NDG hALB mice but not in B-NDG mice (B). In addition, human plasma was collected and assayed for human ALB expression levels as a reference (C).