B-hα4β7 mice

C57BL/6-Itga4tm1(ITGA4)Bcgen Itgb7tm1(ITGB7)Bcgen/Bcgen • 111913

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B-hα4β1 mice
B-hα4β7/hIL7R mice

B-hα4β7 mice

Product nameB-hα4β7 mice
Catalog number111913
Strain nameC57BL/6-Itga4tm1(ITGA4)Bcgen Itgb7tm1(ITGB7)Bcgen/Bcgen
Strain backgroundC57BL/6
Aliasesintegrin subunit alpha 4, CD49D, IA4; integrin subunit beta 7, Ly69
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  • Phenotypic analysis

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      Protein expression analysis-DCs

      Strain specific ITGA4 and ITGB7 expression analysis in homozygous B-hα4β7 mice by flow cytometry.Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hα4β7 mice (H/H; H/H). Mouse ITGA4 and ITGB7 were exclusively detectable in wild-type C57BL/6 mice. Human ITGA4 and ITGB7 were exclusively detectable in homozygous B-hα4β7 mice.

      Protein expression analysis-NK cells
      Strain specific ITGA4 and ITGB7 expression analysis in homozygous B-hα4β7 mice by flow cytometry.Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hα4β7 mice (H/H; H/H). Mouse ITGA4 and ITGB7 were exclusively detectable in wild-type C57BL/6 mice. Human ITGA4 and ITGB7 were exclusively detectable in homozygous B-hα4β7 mice.
      Protein expression analysis-Monocytes
      Strain specific ITGA4 and ITGB7 expression analysis in homozygous B-hα4β7 mice by flow cytometry.Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hα4β7 mice (H/H; H/H). Mouse ITGA4 and ITGB7 were exclusively detectable in wild-type C57BL/6 mice. Human ITGA4 and ITGB7 were exclusively detectable in homozygous B-hα4β7 mice.
      Protein expression analysis-Macrophages
      Strain specific ITGA4 and ITGB7 expression analysis in homozygous B-hα4β7 mice by flow cytometry.Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hα4β7 mice (H/H; H/H). Mouse ITGA4 and ITGB7 were exclusively detectable in wild-type C57BL/6 mice. Human ITGA4 and ITGB7 were exclusively detectable in homozygous B-hα4β7 mice.