B-hPD-1/hBTLA mice

C57BL/6-Pdcd1tm1(PDCD1)Bcgen Btlatm1(BTLA)Bcgen/Bcgen • 120517

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B-hPD-1/hBTLA mice

Product nameB-hPD-1/hBTLA mice
Catalog number120517
Strain nameC57BL/6-Pdcd1tm1(PDCD1)Bcgen Btlatm1(BTLA)Bcgen/Bcgen
Strain backgroundC57BL/6
NCBI gene ID18566,208154
AliasesPD-1 (Programmed death-1);BTLA (B and T lymphocyte associated)

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  • Phenotypic analysis

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      mRNA expression analysis
      Protein Expression Analysis

      Splenocytes from both wild type (WT) C57BL/6 and homozygous B-hPD-1/hBTLA mice were analyzed by flow cytometry. Mouse BTLA+ B cells were detectable in the WT C57BL/6 mice, while human BTLA+ B cells were detectable in the homozygous B-hPD-1/hBTLA mice.

      Splenocytes from both wild type (WT) C57BL/6 and homozygous B-hPD-1/hBTLA mice were by flow cytometry. Mouse PD-1+ T cells were detectable in the WT C57BL/6 mice, while human PD-1+ T cells were detectable in the homozygous B-hPD-1/hBTLA mice.