B-Grpr-iCre mice

C57BL/6-Grprtm1(icre)Bcgen/Bcgen • 110125

B-Grpr-iCre mice

Product nameB-Grpr-iCre mice
Catalog number110125
Strain nameC57BL/6-Grprtm1(icre)Bcgen/Bcgen
Strain backgroundC57BL/6
NCBI gene ID14829
Official symbolGrpr(gastrin releasing peptide receptor), GR; GRP-R
ChromosomeX
ApplicationB-Grpr-iCre mice

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  • Targeting strategy
  • Phenotypic analysis

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      Gene editing strategy
      An F2A-iCre sequence cassette was placed between the coding sequence of exon 3 and 3’UTR of the Grpr gene in C57BL/6 ES cells. This strain was maintained on a C57BL/6 genetic background.
      Phenotype Analysis

      (I) Schematic depicting virus and retrobeads injection, as well as recording configuration in spinal slices. (J) All recorded cells were filled with biocytin (blue) and were beads-positive (red). GRPR+ fibers were labeled with EYFP (green). Scale bar, 10 mm.