C57BL/6-Gt(ROSA)26Sortm1(CAG-tdTomato)Bcgen/Bcgen • 110148
| Product name | B-CAG-tdTomato cKImice |
|---|---|
| Catalog number | 110148 |
| Strain name | C57BL/6-Gt(ROSA)26Sortm1(CAG-tdTomato)Bcgen/Bcgen |
| Strain background | C57BL/6N |
| Official symbol | ROSA26、tdTomato |
| Chromosome | 6 |
| Application | This CAG-tdTomatomodel is an efficient tool to study the tissue specification of Cre mice, whencross with the Cre mice. |
DescriptionROSAS26 gene produces a long non-coding RNA (lncRNA) that is under the control of a constitutive promoter. This locus is a widely used site for the integration of transgenes and reporter constructs.
Gene editing strategy
Phenotype Analysis
E
Experimental design : T cells were isolated from peripheral blood in the single positive mice and the double-positive mice. The proportion of lymphocyte subpopulation were analyzed by flow cytometry.
Results: tdTomato+ cells were detected in the double-positive mice.
Experimental design : T cells were isolated from spleen in single positive mice and the double-positive mice. The proportion of lymphocyte subpopulation were analyzed by flow cytometry.
Results: tdTomato+ cells were detected in the double-positive mice.
