B-hB2M/HLA-G mice

C57BL/6N-B2mtm1(B2M/HLA-G)Bcgen/Bcgen • 111339

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B-hB2M/HLA-G mice

Product nameB-hB2M/HLA-G mice
Catalog number111339
Strain nameC57BL/6N-B2mtm1(B2M/HLA-G)Bcgen/Bcgen
Strain backgroundC57BL/6N
AliasesHLA-G

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  • Phenotypic analysis

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      Protein expression analysis
      Strain specific hB2M expression analysis in heterozygous B-hB2M/HLA-G (H/+) mice by flow cytometry. Splenocytes were collected from wild-type mice (+/+) and heterozygous B-hB2M/HLA-G (H/+) mice, and analyzed by flow cytometry with species-specific anti-B2M antibody. Mouse B2M was detectable in wild-type mice and heterozygous B-hB2M/HLA-G (H/+). Human B2M was exclusively detectable in heterozygous B-hB2M/HLA-G (H/+) mice but not wild-type mice.
      Strain specific HLA-G expression analysis in heterozygous B-hB2M/HLA-G (H/+) mice by flow cytometry. Splenocytes were collected from wild-type mice (+/+) and heterozygous B-hB2M/HLA-G mice (H/+) ,and analyzed by flow cytometry with species-specific anti-HLA-G antibody. Human HLA-G was exclusively detectable in heterozygous B-hB2M/HLA-G (H/+) but not in wild-type mice.