B-hCD155 mice

C57BL/6-Cd155tm1(CD155)Bcgen/Bcgen • 110759

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B-hCD155 mice

Product nameB-hCD155 mice
Catalog number110759
Strain nameC57BL/6-Cd155tm1(CD155)Bcgen/Bcgen
Strain backgroundC57BL/6
NCBI gene ID52118
AliasesPVR, HVED, NECL5, Necl-5, PVS, TAGE4

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  • Phenotypic analysis

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      mRNA expression analysis

      Strain specific analysis of CD155 gene expression in wild type (WT) and B-Hcd155 mice by RT-PCR.
      Mouse Cd155 mRNA was detectable only in splenocytes of wild type (+/+) mice. Human CD155 mRNA was detectable only in homozygous B-hCD155 but not in wild-type mice.

      Protein expression analysis

      Strain specific CD155 expression analysis in homozygous B-hCD155 mice by flow cytometry.
      Peritoneal washing macrophages were collected from wild-type (+/+) and homozygous B-hCD155 (H/H) mice and analyzed by flow cytometry with species-specific anti-CD155 antibody. Mouse CD155 was detectable in wild-type mice. Human CD155 was exclusively detectable in homozygous B-hCD155 but not in wild-type mice.

      The expression of CD155 in tissues of B-hCD155 mice (female)

      The expression of CD155 in tissues of B-hCD155 mice. Different levels of hCD155 positive signals can be detected in the heart, liver, spleen, lung, kidney, pancreas, thymus, salivary gland, duodenum, jejunum, ileum, colon, ovary, lymph node, bladder and brain of B-hCD155 mice. Positive control: NUGC4; Negative control: C57BL/6 wild-type mice.The symbol in the upper left corner represents signal strength (-~+++). No positive staining (-), suspicious positivity (±), weakly positive (+), moderately positive (++), and strongly positive (+++).

      The expression of CD155 in tissues of B-hCD155 mice (male)

      The expression of CD155 in tissues of B-hCD155 mice. Different levels of hCD155 positive signals can be detected in the heart, liver, spleen, lung, kidney, pancreas, thymus, salivary gland, duodenum, jejunum, ileum, colon, prostate gland, lymph node, bladder, testis and brain of B-hCD155 mice. Positive control: NUGC4; Negative control: C57BL/6 wild-type mice.

      The expression of CD155 in tissues of human

      The expression of CD155 in tissues of human. Different levels of hCD155 positive signals can be detected in the heart, liver, spleen, lung, kidney, pancreas, thymus, salivary gland, colon, ovary, prostate gland, testis, lymph node, bladder and brain of human.