C57BL/6N-Fzd7tm1(FZD7)Bcgen/Bcgen • 112674
| Product name | B-hFZD7 mice |
|---|---|
| Catalog number | 112674 |
| Strain name | C57BL/6N-Fzd7tm1(FZD7)Bcgen/Bcgen |
| Strain background | C57BL/6N |
| Aliases | FZD7:FzE3 |
Targeting strategyGene targeting strategy for B-hFZD7 mice. The exon of mouse Fzd7 gene that encodes the full-length protein was replaced by human FZD7 exon in B-hFZD7 mice.
Protein expression analysis
Western blot analysis of FZD7 protein expression in homozygous B-hFZD7 mice. Various tissue lysates were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hFZD7 mice (H/H), and then analyzed by western blot with anti-FZD7 antibody. 40 μg total proteins were loaded for western blotting analysis. FZD7 was detected in heart, brain and skeletal muscle. The antibody cross recognizes human and mouse FZD7.
mRNA expression analysis
