C57BL/6N-Il19tm1(IL19)Bcgen/Bcgen • 111597
| Product name | B-hIL19 mice |
|---|---|
| Catalog number | 111597 |
| Strain name | C57BL/6N-Il19tm1(IL19)Bcgen/Bcgen |
| Strain background | C57BL/6N |
| Aliases | IL-10C, MDA1, NG.1, ZMDA1 |
Targeting strategyGene targeting strategy for B-hIL19 mice. The exons 2-6 of mouse Il19 gene that encode the full coding sequences were replaced by human IL19 exons 2-6 in B-hIL19 mice.
mRNA expression analysis
Protein expression analysis
Strain specific IL19 expression analysis in homozygous B-hIL19 mice by ELISA. Plasma were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hIL19 mice (H/H) stimulated with or without LPS in vivo and analyzed by ELISA with strain-specific anti-IL19 ELISA kit. Mouse IL19 was only detectable in wild-type mice. Human IL19 was only detectable in homozygous B-hIL19 mice.
