B-hITGAL mice

C57BL/6-Itgaltm1(ITGAL)Bcgen/Bcgen • 111389

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B-hITGAL mice

Product nameB-hITGAL mice
Catalog number111389
Strain nameC57BL/6-Itgaltm1(ITGAL)Bcgen/Bcgen
Strain backgroundC57BL/6
AliasesITGAL: CD11A, LFA-1, LFA1A

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  • Phenotypic analysis

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      Protein expression analysis

      Strain specific ITGAL expression analysis in wild-type C57BL/6 and homozygous B-hITGAL mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 (+/+) and homozygous B-hITGAL mice (H/H) and analyzed by flow cytometry with species-specific anti-ITGAL antibody. Mouse ITGAL was detectable only in T, B and NK cells in wild-type mice, and hITGAL was exclusively detectable in T, B and NK cells in homozygous mice.

      Strain specific ITGAL expression analysis in wild-type C57BL/6 and homozygous B-hITGAL mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 (+/+) and homozygous B-hITGAL mice (H/H) and analyzed by flow cytometry with species-specific anti-ITGAL antibody. Mouse ITGAL was detectable only in DCs, neutrophils, monocytes and macrophages in wild-type mice, and hITGAL was exclusively detectable in DCs, neutrophils, monocytes and macrophages in homozygous mice.

      Protein expression profiles of ITGAL

      Strain specific ITGAL expression analysis in wild-type C57BL/6 and homozygous B-hITGAL mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 (+/+) and homozygous B-hITGAL mice (H/H) and analyzed by flow cytometry with species-specific anti-ITGAL antibody. Mouse ITGAL was detectable in T, B, NK cells, DCs, neutrophils, monocytes and macrophages in wild-type mice, and hITGAL was exclusively detectable in T, B, NK cells, DCs, neutrophils, monocytes and macrophages in homozygous mice.