B-hPD-1/hPD-L1/hLAG3 plus/hVSIG4 mice

C57BL/6-Pdcd1tm1(PDCD1)Bcgen Cd274tm1(CD274)Bcgen Lag3tm3(LAG3)Bcgen Vsig4tm3(VSIG4)Bcgen/Bcgen • 113107

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B-hPD-1/hPD-L1/hLAG3 plus/hVSIG4 mice

Product nameB-hPD-1/hPD-L1/hLAG3 plus/hVSIG4 mice
Catalog number113107
Strain nameC57BL/6-Pdcd1tm1(PDCD1)Bcgen Cd274tm1(CD274)Bcgen Lag3tm3(LAG3)Bcgen Vsig4tm3(VSIG4)Bcgen/Bcgen
Strain backgroundC57BL/6
NCBI gene ID18566,60533,16768,278180
AliasesPDCD1: CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1CD274: B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, hPD-L1LAG3: CD223VSIG4: CRIg, Z39IG
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      B-hPD-1/hPD-L1/hLAG3 plus/hVSIG4 mice were derived from mating B-hPD-1/hPD-L1/hLAG3 plus mice (130572) and B-hVSIG4 mice (111035) together. For validation data of this mouse model, you can refer to the validation data from the related gene humanized mouse models.