C57BL/6-Il27ratm1(IL27RA)Bcgen/Bcgenn • 110765
Product name | B-hIL27RA mice |
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Catalog number | 110765 |
Strain name | C57BL/6-Il27ratm1(IL27RA)Bcgen/Bcgenn |
Strain background | C57BL/6 |
NCBI gene ID | 50931 |
Aliases | CRL1, IL-27RA, IL27R, TCCR, WSX1, zcytor1 |
Gene targeting strategy for B-hIL27RA mice. The extracellular gene sequences of mouse Il27ra gene were replaced with human IL27RA counterpart gene in B-hIL27RA mice.
Strain specific analysis of IL27RA gene expression in wild-type mice and B-hIL27RA mice by RT-PCR. Mouse IL27RA mRNA was detectable in the spleen of wild-type mice (+/+). Human IL27RA mRNA was detectable only in homozygous B-hIL27RA mice but not in wild-type mice.